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Genereic Aldactone 100 mg comes in boxes, each unit containing 100 pills (100 mg/pill). Patients who tolerate 25 mg once daily may have their dosage increased to 50 mg once daily as clinically indicated Aldactone (spironolactone) is a prescription diuretic used to remove the excess fluid caused by congestive heart failure, cirrhosis of the liver, and kidney disease. By lowering the high blood pressure, this medicine prevents further life risk complications like strokes, heart attacks, and kidney failures. Spironolactone is a medication often used as a diuretic or for treatment of heart failure. Taking this medicine with other drugs that make you dizzy or lower your blood pressure can worsen these effects. 1-15 business days. Save up to 80% by paying online and then choose free delivery or free pickup at your local pharmacy. Produced by Pfizer, the patents for Aldactone expired in 1982 and 1983. 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